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Article

Clustered mutations in the second exon of the MYC gene in sporadic Burkitt's lymphoma.

Oncogene - 1 Oct 1993

Yano T, Sander C A, Clark H M, Dolezal M V, Jaffe E S, Raffeld M

Abstract excerpt

The primary tumors from 15 untreated patients with Burkitt's lymphoma were analysed for abnormalities in the coding region of the MYC gene by single stranded conformational polymorphism (SSCP) analysis followed by DNA sequencing. Fourteen of the 15 tumors had one or more clonal mutations. Forty one mutations were found in the second exon; only one occurred in the third exon. Seven tumors had mutations that...

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Identifiers

PMID: 8397370

Genes

MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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