Non-mutagenic nitroheterocycles. The lack of correlation between bacterial mutagenicity and one-electron reduction potential.

doi:10.1016/0165-1218(83)90127-1

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Article

Non-mutagenic nitroheterocycles. The lack of correlation between bacterial mutagenicity and one-electron reduction potential.

Mutation research - 1 Jan 2000

Hartman G D, Hartman R D

Abstract excerpt

The bacterial mutagenicity (Ames test) and the one-electron reduction potential for several nitropyridines, nitropyrazines and nitropyrimidines were determined. It was found that, although these nitroheterocycles underwent one-electron reduction more easily than metronidazole, they were not mutag...

Topics

Electrons
Mutagenicity Tests
Mutagens
Mutation
Oxidation-Reduction
Salmonella typhimurium
Structure-Activity Relationship

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