Article
Salmonella/microsome mutagenicity of 1-nitropyrene-2-ol, a nitropyrene phenol formed in the photolysis of 1-nitropyrene.
Zeitschrift fur Naturforschung. Section C, Biosciences - 1 Jan 2000
Löfroth G, Nilsson L, Agurell E, Yasuhara A
Abstract excerpt
1-Nitropyrene-2-ol is not detectably mutagenic in the Salmonella test in the absence of mammalian activation. It is activated by the rat liver microsome-containing preparation S9 and gives a mutagenic response similar to that of benzo(a)pyrene.
Topics
- Animals
- Biotransformation
- Male
- Mice
- Microsomes, Liver
- Mutagenicity Tests
- Mutagens
- Mutation
- Photolysis
- Pyrenes
- Rats
- Rats, Inbred Strains
- Salmonella