Genotoxicity of p-nitrocinnamaldehyde and related alpha, beta-unsaturated carbonyl compounds in two bacterial assays.

doi:10.1093/mutage/6.4.261

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Article

Genotoxicity of p-nitrocinnamaldehyde and related alpha, beta-unsaturated carbonyl compounds in two bacterial assays.

Mutagenesis - 1 Jul 1991

Eder E, Deininger C, Muth D

Abstract excerpt

Seventeen cinnamaldehydes, cinnamic acids, 2-furylacroleins and related compounds were tested in the Salmonella preincubation reversion assay and in the SOS chromotest. Of eight compounds containing nitrogroups, seven were clearly mutagenic in the presence of S9 mix and six in its absence; wherea...

Topics

Acrolein
Biotransformation
Escherichia coli
Frameshift Mutation
Mutagenesis
Mutagenicity Tests
Mutation
Nitroreductases
SOS Response, Genetics
Salmonella typhimurium
Structure-Activity Relationship

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