Article
Reactivity of the mutagen 1,4-dinitro-2-methylpyrrole as an alkylating agent.
The Journal of organic chemistry - 5 Mar 2010
Pérez-Prior M Teresa, Gómez-Bombarelli Rafael, González-Pérez Marina, Manso José A, García-Santos M Pilar, Calle Emilio, Casado Julio
Abstract excerpt
The formation of chemical species with DNA-damaging and mutagenic activity for bacterial test systems was detected in sorbic acid-nitrite mixtures. 1,4-Dinitro-2-methylpyrrole (NMP), one the main products resulting from the reaction between sorbic acid and nitrite, has mutagenic properties, and h...
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