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Article

Reactivity of the mutagen 1,4-dinitro-2-methylpyrrole as an alkylating agent.

The Journal of organic chemistry - 5 Mar 2010

Pérez-Prior M Teresa, Gómez-Bombarelli Rafael, González-Pérez Marina, Manso José A, García-Santos M Pilar, Calle Emilio, Casado Julio

Abstract excerpt

The formation of chemical species with DNA-damaging and mutagenic activity for bacterial test systems was detected in sorbic acid-nitrite mixtures. 1,4-Dinitro-2-methylpyrrole (NMP), one the main products resulting from the reaction between sorbic acid and nitrite, has mutagenic properties, and here its alkylating capacity was investigated. The conclusions drawn are as follows: (i) In aqueous medium, after the...

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PMID: 20121054
DOI: 10.1021/jo902329q

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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