Article
Hypogammaglobulinaemia in systemic lupus erythematosus: report of a case with evidence for spontaneously activated T suppressor cells.
Clinical and experimental rheumatology - 1 Jan 2000
Peters J, Astrup L, Andersen V
Abstract excerpt
A patient with hypogammaglobulinaemia associated with systemic lupus erythematosus (SLE), a healthy HLA-A, B, C, D-identical and mixed lymphocyte culture (MLC)-negative sibling, and two mutually HLA-A, B, C, D-identical siblings were investigated. Blood mononuclear cells from the patient contained a high proportion of T lymphocytes with the suppressor/cytotoxic phenotype, and in vitro no development of...
Topics
- Adult
- Agammaglobulinemia
- Female
- HLA Antigens
- Humans
- Hypergammaglobulinemia
- Lupus Erythematosus, Systemic
- Macrophages
- Phenotype
- Pokeweed Mitogens
- T-Lymphocytes
