Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Altered T cell subpopulations and lymphocytes expressing natural killer cell phenotypes in patients with progressive systemic sclerosis.

The Journal of allergy and clinical immunology - 1 Apr 1991

Frieri M, Angadi C, Paolano A, Oster N, Blau S P, Yang S, Mele C, Hawrylko E

Abstract excerpt

Scleroderma (progressive systemic sclerosis [PSS]) is known to be associated with abnormal T cell immunoregulation. In the present study, we evaluated lymphocyte phenotypes in patients with PSS and normal control subjects by flow cytometry and monoclonal antibodies for total T (CD3), T suppressor (CD8), T helper (CD4), T helper-inducer (CDw29), T suppressor-inducer (CD45R), human leukocyte antigen, DR+B (CD19),...

Topics

Adult
Aged
Arthritis, Rheumatoid
Female
Humans
Killer Cells, Natural
Male
Middle Aged
Phenotype
Scleroderma, Systemic
T-Lymphocyte Subsets

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 2013671
DOI: 10.1016/0091-6749(91)90121-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2013671-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Altered T cell subpopulations and lymphocytes expressing natural killer cell phenotypes in patients with progressive systemic sclerosis.PMID 2013671Read ↗

Alterations in peripheral T- and B-cell subsets in patients with systemic sclerosis.Semantic proximity Read ↗

Phenotypic characteristics of dissociated mononuclear cells from rheumatoid synovial membrane.Semantic proximity Read ↗

Association of immunological cell profiles with specific clinical phenotypes of scleroderma disease.Semantic proximity Read ↗

CD4+ and CD8+ subsets: naive and memory cells in the peripheral blood of patients with systemic sclerosis.Semantic proximity Read ↗

Phenotypic abnormalities in CD8+ T lymphocyte subsets in patients with rheumatoid arthritis.Semantic proximity Read ↗

Lymphocyte subset abnormalities in early severe scleroderma favor a Th2 phenotype and are not altered by prior immunosuppressive therapy.Semantic proximity Read ↗

Reduced circulating regulatory T cells in primary Sjögren’s syndrome: the contribution of enhanced apoptosis and impaired survivalSemantic proximity Read ↗

Reduced proportions of natural killer T cells are present in the relatives of lupus patients and are associated with autoimmunity.Semantic proximity Read ↗

A <scp>PD‐1<sup>high</sup>CD4</scp><sup>+</sup> T Cell Population With a Cytotoxic Phenotype is Associated With Interstitial Lung Disease in Systemic SclerosisSemantic proximity Read ↗

NCR3/NKp30 contributes to pathogenesis in primary Sjogren's syndrome.Semantic proximity Read ↗

Reduced non-switched memory B cell subsets cause imbalance in B cell repertoire in systemic sclerosis.Semantic proximity Read ↗

Abnormalities in bone marrow mononuclear cells in patients with rheumatoid arthritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.