The effect of methylprednisolone on lymphocyte phenotype and function in patients with multiple sclerosis.

doi:10.1016/0165-5728(90)90114-3

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Article

The effect of methylprednisolone on lymphocyte phenotype and function in patients with multiple sclerosis.

Journal of neuroimmunology - 1 Jan 1990

Kirk P, Compston A

Abstract excerpt

The extent to which symptomatic improvement in patients with multiple sclerosis treated with intravenous methylprednisolone depends on immunological actions of corticosteroids is unknown. In this study the effect of methylprednisolone on circulating T and B cell function has been assessed in vitr...

Topics

CD4-Positive T-Lymphocytes
Cells, Cultured
Concanavalin A
Female
Humans
Immunoglobulin G
Leukocyte Count
Lymphocytes
Male
Methylprednisolone
Middle Aged
Multiple Sclerosis
Phenotype
Pokeweed Mitogens
Reference Values
T-Lymphocytes, Regulatory

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