Article
Functional defects in peripheral blood T cells of multiple sclerosis patients. Diminished in vitro responsiveness in accessory cell dependent activation systems.
Journal of neuroimmunology - 1 Jul 1994
Rep M H, Hintzen R Q, Polman C H, van Lier R A
Abstract excerpt
Function and phenotype of peripheral blood (PB) T cells in multiple sclerosis (MS) patients were analyzed. In whole blood cultures, T cell proliferation of multiple sclerosis (MS) patients, using soluble CD3 mAb and CD2 mAb as stimulants, was reduced in comparison to healthy controls. A similar d...
Topics
- Adult
- Aged
- Antigen-Presenting Cells
- Blood Cells
- Cells, Cultured
- Female
- Humans
- Lymphocyte Activation
- Lymphocyte Subsets
- Male
- Middle Aged
- Multiple Sclerosis
- Phenotype
- Reference Values
- T-Lymphocytes