Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional T cell subpopulations responsible for hyposecretion of IL-2 in patients with systemic lupus erythematosus.

Clinical rheumatology - 1 Dec 1991

Hayama T, Kubo N, Ikeda E, Hashimoto H, Sawada S, Horie T

Abstract excerpt

The ability of T cells to secrete IL-2 in patients with systemic lupus erythematosus (SLE) was investigated. In patients with SLE, impaired IL-2 production by peripheral blood lymphocytes stimulated with mitogens is well known. In this paper, we report that purified T cells stimulated with mitogens, in the presence of Epstein-Barr virus transformed B cells (B-LCL) as an accessory cell, however, could secrete a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Blood Cells
Share to Cell Aggregation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Interleukin-2

Share to Lupus Erythematosus, Systemic

Share to Lymphocyte Subsets

Share to Phenotype

Share to T-Lymphocytes

Source

Identifiers

PMID: 1802493
DOI: 10.1007/BF02206658

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Functional T cell subpopulations responsible for hyposecretion of IL-2 in patients with systemic lupus erythematosus.PMID 1802493Read ↗

Hypogammaglobulinaemia in systemic lupus erythematosus: report of a case with evidence for spontaneously activated T suppressor cells.Semantic proximity Read ↗

Functional defects in peripheral blood T cells of multiple sclerosis patients. Diminished in vitro responsiveness in accessory cell dependent activation systems.Semantic proximity Read ↗

Exogenous interleukin 2 (IL 2) reconstitutes deficient in vitro T-cell growth of patients with chronic lymphocytic leukemia of B-cell lineage (B-CLL).Semantic proximity Read ↗

B cell hyperactivity is a function of T cell derived cytokines in systemic lupus erythematosus.Semantic proximity Read ↗

CD4+ Group 1 Innate Lymphoid Cells (ILC) Form a Functionally Distinct ILC Subset That Is Increased in Systemic SclerosisSemantic proximity Read ↗

Functional differentiation and regulation of follicular T helper cells in inflammation and autoimmunity.Semantic proximity Read ↗

Pathways leading to an immunological disease: systemic lupus erythematosus.Semantic proximity Read ↗

Inability to produce IL-6 is a functional feature of human germinal center B lymphocytes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.