Article
Immunologic effects of plasmapheresis synchronized with pulse cyclophosphamide in systemic lupus erythematosus.
The Journal of rheumatology - 1 Feb 1991
Dau P C, Callahan J, Parker R, Golbus J
Abstract excerpt
Extensive immunologic evaluation was made of a patient with severe systemic lupus erythematosus (SLE) undergoing 6 cycles of plasmapheresis combined with pulsed cyclophosphamide therapy. Clinical remission ensued accompanied by normalization of levels of circulating autoantibodies, immune complexes, complement proteins, interleukin 2 (IL-2) and IL-2 receptor. High spontaneous peripheral blood lymphocyte...
Topics
- Adult
- Antigen-Antibody Complex
- Autoantibodies
- B-Lymphocytes
- Cell Division
- Complement System Proteins
- Cyclophosphamide
- Dose-Response Relationship, Drug
- Female
- Humans
- Immunoglobulin G
