Article
Responses to the H-2Kba mutant involve recognition of syngeneic Ia molecules.
Nature - 1 Jan 2000
Weinberger O, Germain R N, Burakoff S J
Abstract excerpt
Conventional antigens appear to be recognized by T lymphocytes only when associated with major histocompatibility complex (MHC) antigens. Using antigen-specific proliferation as a model for helper T lymphocytes, it has been demonstrated that Ly1+T cells recognize antigen presented in association with syngeneic Ia molecules. In contrast to responses to conventional antigens, however, a large number of studies have...
Topics
- Animals
- Cytotoxicity, Immunologic
- H-2 Antigens
- Histocompatibility Antigens Class II
- Lymphocyte Activation
- Lymphocyte Cooperation
- Mice
- Mutation
- T-Lymphocytes
- T-Lymphocytes, Helper-Inducer