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Article

Unique biochemical properties of a mutant MHC class I molecule, H-2Ksm1.

Molecular immunology - 1 Dec 1992

Hasenkrug K J, Kesari K V, Nathenson S G

Abstract excerpt

This study describes serological and biochemical properties of a novel MHC class I molecule. The mutant H-2Ksm1 molecule was discovered in a mouse because of loss of reactivity of its peripheral blood lymphocytes to monoclonal antibodies. This mutation in the H-2Ks molecule is the first in vivo mutation described that has altered an amino acid residue (amino acid 107) distant from the regions generally considered...

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PMID: 1280760
DOI: 10.1016/0161-5890(92)90223-k

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