Unique biochemical properties of a mutant MHC class I molecule, H-2Ksm1.

doi:10.1016/0161-5890(92)90223-k

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Article

Unique biochemical properties of a mutant MHC class I molecule, H-2Ksm1.

Molecular immunology - 1 Dec 1992

Hasenkrug K J, Kesari K V, Nathenson S G

Abstract excerpt

This study describes serological and biochemical properties of a novel MHC class I molecule. The mutant H-2Ksm1 molecule was discovered in a mouse because of loss of reactivity of its peripheral blood lymphocytes to monoclonal antibodies. This mutation in the H-2Ks molecule is the first in vivo m...

Topics

Animals
Antibody-Dependent Cell Cytotoxicity
Base Sequence
Blotting, Northern
Cold Temperature
Dose-Response Relationship, Immunologic
Electrophoresis, Polyacrylamide Gel
Flow Cytometry
H-2 Antigens
Liver
Mice
Mice, Inbred Strains
Molecular Sequence Data
Mutation
Oligonucleotide Probes
RNA
Spleen
beta 2-Microglobulin

Source

Open in PubMed

Identifiers

PMID: 1280760
DOI: 10.1016/0161-5890(92)90223-k

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1280760-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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