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Article

Idiotypes of anti-phosphocholine antibodies: structural correlates.

Annales d'immunologie - 1 Jan 2000

Maddalena A, Hudak S, Claflin J L

Abstract excerpt

Phosphocholine-specific antibodies in mice are composed of three families of antibodies, the T15, the M603 and the M511, which are constructed by combinatorial association of a VH4 H chain and one of three different L chains, VK22, VK8 and VK24, respectively. Antiidiotypic antisera can be generated which (1) recognize all members of a family, i. e. anti-T15 IdX, anti-M603 IdX and anti-M511 IdX, (2) distinguish...

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PMID: 6201128
DOI: 10.1016/s0769-2625(84)80020-3

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