Article
Idiotope structure and genetic diversity in anti-streptococcal group A carbohydrate antibodies.
Journal of immunology (Baltimore, Md. : 1950) - 1 Aug 1990
Phillips N J, Davie J M
Abstract excerpt
Three cross-reactive idiotopes(Id), termed IdX, IdI-1, and Id5, that are present on free L chains from murine anti-group A streptococcal carbohydrate antibodies have been mapped; these Id distinguish between products of three homologous V kappa genes. For each determinant, sequence analysis of an...
Topics
- Amino Acid Sequence
- Animals
- Antibodies, Bacterial
- Carbohydrates
- Genetic Variation
- Immunoglobulin Idiotypes
- Immunoglobulin Light Chains
- Mice
- Molecular Sequence Data
- Streptococcus pyogenes