Article
Idiotope structure and genetic diversity in anti-streptococcal group A carbohydrate antibodies.
Journal of immunology (Baltimore, Md. : 1950) - 1 Aug 1990
Phillips N J, Davie J M
Abstract excerpt
Three cross-reactive idiotopes(Id), termed IdX, IdI-1, and Id5, that are present on free L chains from murine anti-group A streptococcal carbohydrate antibodies have been mapped; these Id distinguish between products of three homologous V kappa genes. For each determinant, sequence analysis of anti-streptococcal group A carbohydrate antibody V domains yielded small numbers of amino acids invariably associated...
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