Article
Mechanisms of disease: The genetic basis of coronary heart disease.
Nature clinical practice. Cardiovascular medicine - 1 Oct 2007
Kullo Iftikhar J, Ding Keyue
Abstract excerpt
Since completion of the human genome sequence, considerable progress has been made in determining the genetic basis of human diseases. Understanding the genetic basis of coronary heart disease (CHD), the leading cause of mortality in developed countries, is a priority. Here we provide an update on the genetic basis of CHD, focusing mainly on the clinical manifestations rather than the risk factors, most of which...
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