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Utility of genetic and non-genetic risk factors in predicting coronary heart disease in Singaporean Chinese.

European journal of preventive cardiology - 1 Jan 2017

Chang Xuling, Salim Agus, Dorajoo Rajkumar, Han Yi, Khor Chiea-Chuen, van Dam Rob M, Yuan Jian-Min, Koh Woon-Puay, Liu Jianjun, Goh Daniel Yt, Wang Xu, Teo Yik-Ying, Friedlander Yechiel, Heng Chew-Kiat

Abstract excerpt

Background Although numerous phenotype based equations for predicting risk of 'hard' coronary heart disease are available, data on the utility of genetic information for such risk prediction is lacking in Chinese populations. Design Case-control study nested within the Singapore Chinese Health Study. Methods A total of 1306 subjects comprising 836 men (267 incident cases and 569 controls) and 470 women (128...

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PMID: 27799596
DOI: 10.1177/2047487316676609

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