Article
Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.
Circulation research - 2 Feb 2018
van der Harst Pim, Verweij Niek
Abstract excerpt
RATIONALE: Coronary artery disease (CAD) is a complex phenotype driven by genetic and environmental factors. Ninety-seven genetic risk loci have been identified to date, but the identification of additional susceptibility loci might be important to enhance our understanding of the genetic architecture of CAD. OBJECTIVE: To expand the number of genome-wide significant loci, catalog functional insights, and enhance...
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