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Article

Genetics and Genomics of Coronary Artery Disease: What We Have Learned.

The Canadian journal of cardiology - 1 May 2026

McPherson Ruth

Abstract excerpt

Research over the past 2 decades has provided a broader understanding of the genetic architecture of coronary artery disease (CAD) and shows that it derives in large part from the cumulative effect of multiple common risk alleles that are individually of small effect size but cumulatively have large effects on CAD risk. The tools applied include genome-wide association study (GWAS), which encompasses thousands of...

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Identifiers

PMID: 42161473
DOI: 10.1016/j.cjca.2026.01.051

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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