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Article

Exploring the genetic correlation between inflammatory bowel disease and psychiatric disorders: insights from genome-wide association studies.

European archives of psychiatry and clinical neuroscience - 1 Oct 2026

Zhang Jie, Shen Jing, Liu Lifeng

Abstract excerpt

BACKGROUND: Inflammatory bowel disease (IBD) and psychiatric disorders exhibit complex comorbid patterns, with anxiety and depressive disorders being significantly more prevalent in IBD patients compared to the general population. These comorbidities may differ between Crohn's disease (CD) and ulcerative colitis (UC), suggesting heterogeneous but potentially shared genetic mechanisms mediated through the...

Read the complete abstract on PubMed

Topics

Humans
Genome-Wide Association Study
Inflammatory Bowel Diseases
Mental Disorders
Comorbidity
Attention Deficit Disorder with Hyperactivity

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Anxiety Disorders

Genetic Predisposition to Disease

Source

Open in PubMed Open full text

Identifiers

PMID: 42362821
DOI: 10.1007/s00406-026-02302-1
PMCID: PMC13562344

Genes

NOD2
AURKB
IL10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

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