Article

Gut microbial and human genetic signatures of inflammatory bowel disease increase risk of comorbid mental disorders

2023-12-14

Abstract excerpt

The high prevalence of comorbid mental disorders (CMDs), such as anxiety and depression, in patients with inflammatory bowel disease (IBD) is well documented. The reported bidirectional relationship between the two conditions suggests a crucial role of a gut-brain axis in CMD development in patients with IBD. This study aimed to investigate a complex interplay between gut microbiota and host genetic variants relev...

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Literature Corpus work: ada5088c-b7b3-510e-a2ac-331b0484fb0b
DOI: 10.1101/2023.12.13.23299882

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