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Article

Shared genetic basis and causality between schizophrenia and inflammatory bowel disease: evidence from a comprehensive genetic analysis.

Psychological medicine - 1 Jul 2024

Wang Jing, Luo Guang-Yu, Tian Tian, Zhao Yu-Qiang, Meng Shi-Yin, Wu Jun-Hua, Han Wen-Xiu, Deng Bin, Ni Jing

Abstract excerpt

BACKGROUND: The comorbidity between schizophrenia (SCZ) and inflammatory bowel disease (IBD) observed in epidemiological studies is partially attributed to genetic overlap, but the magnitude of shared genetic components and the causality relationship between them remains unclear. METHODS: By leveraging large-scale genome-wide association study (GWAS) summary statistics for SCZ, IBD, ulcerative colitis (UC), and...

Read the complete abstract on PubMed

Topics

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Share to Causality
Share to Colitis, Ulcerative

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Comorbidity

Share to Crohn Disease

Share to Genetic Pleiotropy

Share to Inflammatory Bowel Diseases

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Source

Identifiers

PMID: 38563283
DOI: 10.1017/S0033291724000771

Genes

CSNK1G1
ELP5
KAT5
RABEP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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