Somatic variation in multiple sclerosis: from blood to brain.

Abstract excerpt

Multiple sclerosis (MS) is a progressive autoimmune disease of the central nervous system (CNS) that affects nearly 3 million people worldwide. Pathologically, MS is characterised by inflammation, demyelination and neurodegeneration, leading to declining neurological function and increasing disability. To date, investigations of somatic variation in MS have focused primarily on peripheral immune cells and, more...

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