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Article

HLA-B44 Alleles and HLA-DQA103:01 as Genetic Risk Factors for Drug-Induced Liver Injury due to Fluoroquinolones.

Liver international : official journal of the International Association for the Study of the Liver - 1 Jun 2026

Nicoletti Paola, Lucena M Isabel, Andrade Raul J, Zafer Samreen, Bjornsson Einar S, Hallberg Pär, Larrey Dominique, Molokhia Mariam, Wadelius Mia, Aithal Guruprasad P, Daly Ann K

Abstract excerpt

BACKGROUND AND AIMS: Fluoroquinolone exposure can give rise to drug-induced liver injury. Genetic risk factors for this form of liver injury are poorly understood but some evidence suggests that HLA genes contribute. This study aimed to characterise HLA risk factors for fluoroquinolone-induced liver injury in a European population. METHODS: From the previously described iDILIC cohort, 22 cases of...

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Identifiers

PMID: 42141720
DOI: 10.1111/liv.70699
PMCID: PMC13179464

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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