Article
Genetic risk factors in the development of idiosyncratic drug-induced liver injury.
Expert opinion on drug metabolism & toxicology - 1 Feb 2021
Stephens Camilla, Lucena M Isabel, Andrade Raúl J
Abstract excerpt
Introduction: Idiosyncratic drug-induced liver injury (DILI) is a challenging condition with widespread implications. The underlying mechanism of DILI is not yet fully elucidated, but genetic predispositions are believed to contribute to DILI susceptibility. The identification of genetic risk factors has been a goal in DILI research for more than two decades. Areas covered: Here we provide an overview of genetic...
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