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Article

Human leukocyte antigen genetic risk factors of drug-induced liver toxicology.

Expert opinion on drug metabolism & toxicology - 1 Mar 2015

Grove Jane I, Aithal Guruprasad P

Abstract excerpt

INTRODUCTION: Drug-induced liver injury (DILI) is a rare adverse drug reaction, which impacts significantly on patients. Human leukocyte antigen (HLA) risk alleles have been found to be associated with DILI supporting an immunological basis to DILI pathogenesis. AREAS COVERED: HLA alleles associated with risk of liver injury induced by specific therapeutic drugs are described. The evidence for a role of the...

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Source

Identifiers

PMID: 25491399
DOI: 10.1517/17425255.2015.992414

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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