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Association of mitochondrial genome variants with Alzheimer's disease in a Chinese population.

Journal of Alzheimer's disease : JAD - 1 Jun 2026

Hao Xiaoli, Jiao Bin, Wang Yijing, Xu Tianyan, Yang Qijie, Zhu Yuan, Liu Yiliang, Zhang Cong, Liang Xiaoyan, Zhou Yafang, Liao Xinxin, Luo Shilin, Tang Beisha, Li Jinchen, Xiao Xuewen, Shen Lu

Abstract excerpt

BackgroundResearch on the mitochondrial genome variants of Alzheimer's disease (AD) in Chinese populations is lacking.ObjectiveThe study aimed to identify mitochondrial DNA (mtDNA) variants associated with AD risk and explore the relationship between mtDNA variants and plasma biomarkers in AD patients.MethodsWhole genome sequencing was performed in 1509 AD patients and 2010 controls from the Chinese population....

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PMID: 42104711
DOI: 10.1177/13872877261442231

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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