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Mitochondrial DNA and Alzheimer's disease: a first case-control study of the Tunisian population.

Molecular biology reports - 1 Mar 2022

Ben Salem Nesrine, Boussetta Sami, de Rojas Itziar, Moreno-Grau Sonia, Montrreal Laura, Mokni Narjes, Mahmoud Imene, Younes Samia, Daouassi Nizar, Frih-Ayed Mahbouba, Hammami Afef, Ben Ammar Elgaaied Amel, Ruiz Agustín, Cherni Lotfi

Abstract excerpt

BACKGROUND: Alzheimer's disease (AD) is the most common neurodegenerative disorder in humans and presents a major health problem throughout the world. The etiology of AD is complex, and many factors are implicated, including mitochondria. Mitochondrial alteration has been proposed as a possible cause of AD. Therefore, several studies have focused on finding an association between inherited mitochondrial DNA...

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PMID: 34854014
DOI: 10.1007/s11033-021-06978-7

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