Article
Mitochondrial DNA haplogroup B5 confers genetic susceptibility to Alzheimer's disease in Han Chinese.
Neurobiology of aging - 1 Mar 2015
Bi Rui, Zhang Wen, Yu Dandan, Li Xiao, Wang Hui-Zhen, Hu Qiu-Xiang, Zhang Chen, Lu Weihong, Ni Jianliang, Fang Yiru, Li Tao, Yao Yong-Gang
Abstract excerpt
Mitochondrial dysfunction has been widely reported in psychiatric and neurodegenerative diseases. We aimed to investigate the association between matrilineal structures of Han Chinese populations and Alzheimer's disease (AD) by a 2-stage case-control study: A total of 341 AD patients and 435 normal individuals from Southwest China were analyzed for mitochondrial DNA sequence variations and were classified into...
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