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Mitochondrial DNA variants in a Japanese population of patients with Alzheimer's disease.

Mitochondrion - 1 Jan 2010

Tanaka Noriko, Goto Yu-ichi, Akanuma Jun, Kato Mayuko, Kinoshita Toru, Yamashita Fumio, Tanaka Masashi, Asada Takashi

Abstract excerpt

The evidence for the role of mitochondria in Alzheimer's disease (AD) has been well investigated, based on the amyloid hypothesis and its relation to the mitochondrial dysfunction due to oxidative stress. However, contrasting reports describe an unclear picture on the relationship between AD and mitochondrial DNA (mtDNA) variations. Therefore, we analyzed complete mtDNA sequences from 153 AD patients and 129...

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Source

Identifiers

PMID: 19703591
DOI: 10.1016/j.mito.2009.08.008

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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