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Article

Possible association of mitochondrial transcription factor A (TFAM) genotype with sporadic Alzheimer disease.

Neuroscience letters - 21 Oct 2004

Günther Claudia, von Hadeln Kirsten, Müller-Thomsen Tomas, Alberici Antonella, Binetti Giuliano, Hock Christoph, Nitsch Roger M, Stoppe Gabriela, Reiss Jochen, Gal Andreas, Finckh Ulrich

Abstract excerpt

Mitochondrial transcription factor A (TFAM) is essential for transcription and replication of mammalian mitochondrial DNA (mtDNA). Disturbance of maintenance of mtDNA integrity or mitochondrial function may underlay neurodegenerative disorders such as Alzheimer disease (AD). TFAM, the gene encodi...

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Source

Identifiers

PMID: 15464268
DOI: 10.1016/j.neulet.2004.07.070

Genes

TFAM

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15464268-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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