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Analysis of MED-12 mutations in uterine leiomyomas of Nigerian women.

F&S science - 1 Jul 2026

Rotimi Oluwakemi A, Chionuma Joy O, Koyejo Oluwatosin D, Salami Esther A, Shakunle Adebusola, Okebalama Victor, Makinde Oladimeji, Rotimi Solomon O

Abstract excerpt

OBJECTIVE: To identify, characterize, and determine the frequency of MED-12 exon 2 mutations in the uterine leiomyomas (ULs) of Nigerian women. The MED-12 mutations are the most common molecular subtype of ULs and have been linked with ULs in Western populations. The frequency of MED-12 mutations among Nigerian women has not been established. DESIGN: Cross-sectional study. SUBJECTS: Nigerian women with ULs...

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PMID: 42069218
DOI: 10.1016/j.xfss.2026.04.004

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