Article
Analysis of MED12 Mutation in Multiple Uterine Leiomyomas in South Korean patients.
International journal of medical sciences - 1 Jan 2018
Lee Minkyoung, Cheon Keunyoung, Chae Boah, Hwang Hyesung, Kim Hyun-Kyung, Chung Youn-Jee, Song Jae-Yen, Cho Hyun-Hee, Kim Jang-Heub, Kim Mee-Ran
Abstract excerpt
Uterine leiomyomas are one of the most common benign gynecologic tumors, but the exact causes are not completely understood. In 2011, through DNA sequencing, MED12 mutation was discovered in approximately 71% of uterine leiomyomas. Several recent studies confirmed the high frequency of MED12 mutation in uterine leiomyoma. Nevertheless, no study has been done on MED12 mutation in the case of patients with multiple...
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