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Article

Genetic prediction of blood cell reactivity and its potential causal influence on bone continuity and density disorders.

Animal models and experimental medicine - 1 May 2026

Deng Zhiqin, Zhao Zhe, Jiang Wenting, Chen Xiaoqiang, Liu Jianquan, Tao Xu, Lin Zhengyang, Deng Zhenhan, Li Wencui

Abstract excerpt

BACKGROUND: This study aimed to investigate the potential causal relationship between genetically predicted human blood cell (HBC) reactivity and disorders of bone continuity, density, and structure. METHODS: We analyzed summary-level GWAS data for 91 HBC traits and two bone-related outcomes from publicly available sources, employing the inverse-variance weighted (IVW) method as the principal Mendelian...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41930994
DOI: 10.1002/ame2.70187
PMCID: PMC13331561

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