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Analyzing the causal role of blood cells in aging: a Mendelian randomization study.

Biogerontology - 4 Nov 2024

Zhang Jingjing, Zhang Xin, Xiao Boan, Ouyang Jiecai, Wang Peng, Peng Xiaobin

Abstract excerpt

Blood cells are crucial components of the human body, closely linked to the aging process. This study aims to explore the causal relationship between 91 blood cell phenotypes and aging through Mendelian randomization (MR) analysis. Exposure data from genome-wide association studies (GWAS) was extracted from the GWAS of blood cell perturbation phenotypes in 2,600 European individuals. Initial analysis utilized...

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PMID: 39495328
DOI: 10.1007/s10522-024-10148-0

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