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Article

Causal associations of specific immunoglobulin G N-glycosylation subtypes with osteoporosis: A two-sample Mendelian randomization.

Joint diseases and related surgery - 1 Jan 2026

Zhao Yu, Zhu Yimiao, Zhang Wei, Wang Lijun, Yan Chenyan, Yuan Chaoyun, Wang Lijuan

Abstract excerpt

OBJECTIVES: This study aims to examine whether genetically predicted immunoglobulin G (IgG) N-glycosylation patterns (IGPs) affect osteoporosis risk using a two-sample Mendelian randomization (MR) method. MATERIALS AND METHODS: In a collaborative effort involving the Medical Research Council (MRC) Human Genetics Unit and the FinnGen consortium, we conducted genome-wide association studies (GWAS) to explore the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41391118
DOI: 10.52312/jdrs.2026.2361
PMCID: PMC12788744

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