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Article

Mendelian randomization analysis of the association between human blood cell traits and uterine polyps.

Scientific reports - 4 Mar 2021

Sun Shuliu, Liu Yan, Li Lanlan, Jiao Minjie, Jiang Yufen, Li Beilei, Gao Wenrong, Li Xiaojuan

Abstract excerpt

Human blood cells (HBCs) play essential roles in multiple biological processes but their roles in development of uterine polyps are unknown. Here we implemented a Mendelian randomization (MR) analysis to investigate the effects of 36 HBC traits on endometrial polyps (EPs) and cervical polyps (CPs). The random-effect inverse-variance weighted method was adopted as standard MR analysis and three additional MR...

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Blood Cells
Endometrial Neoplasms
Eosinophils
Genome-Wide Association Study
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Uterine Cervical Neoplasms

Uterine Neoplasms

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Identifiers

PMID: 33664449
DOI: 10.1038/s41598-021-84851-0
PMCID: PMC7933156

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