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Causal Impact of Blood Cell Traits on the Risk of Herpes Zoster: A Two-Sample Mendelian Randomization Study Based on Exogenous Stimulation Data.

Viral immunology - 1 Oct 2026

Li Dongxiao, Gan Junhong, Xiao Lin, Teng Hongli, Xiao Shihai, Liu Ben, Chen Kun, Deng Longpu

Abstract excerpt

Background:Herpes zoster (HZ) is a common neurotropic infectious disease caused by the reactivation of varicella-zoster virus (VZV), primarily triggered by declining host immune function. While circulating immune cells play key roles in antiviral defense, the causal contributions of distinct blood cell functional phenotypes to HZ risk remain unclear.Objective:To investigate potential causal associations between...

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Identifiers

PMID: 42529943
DOI: 10.1177/08828245261474272

Genes

NLRP3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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