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Optimal male fertility and fecundity in Caenorhabditis elegans require Microprocessor and Argonaute gene function.

G3 (Bethesda, Md.) - 3 Jun 2026

Lu Lu, Rios Carmela, Abbott Allison L

Abstract excerpt

Small RNA pathways play key roles in the regulation of gene expression in the germ line and in somatic cells. The germ line in Caenorhabditis elegans has multiple classes of small RNAs that can interact with its 19 Argonaute family proteins, including microRNAs (miRNAs), Piwi-interacting RNAs (piRNAs), and endogenous small interfering RNAs (endo-siRNAs). The pathway for miRNA biogenesis and activity requires...

Topics

Animals
Male
Caenorhabditis elegans
Fertility
Argonaute Proteins
MicroRNAs
Caenorhabditis elegans Proteins
Spermatozoa
Mutation
RNA, Small Interfering

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41928448
DOI: 10.1093/g3journal/jkag079
PMCID: PMC13232498

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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