Article

Two isoforms of the essential <i>C. elegans</i> Argonaute CSR-1 differentially regulate sperm and oocyte fertility

2020-07-21

Abstract excerpt

The C. elegans genome encodes nineteen functional Argonaute proteins that utilize 22G-RNAs, 26G-RNAs, miRNAs, or piRNAs to regulate their target transcripts. Only one Argonaute is essential under normal laboratory conditions: CSR-1. While CSR-1 has been studied widely, nearly all studies have overlooked the fact that the csr-1 locus encodes two isoforms. These isoforms differ by an additional 163 amino acids pre...

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Literature Corpus work: 10fc6f6a-a76b-5c06-a2f5-d63f6ec9883f
DOI: 10.1101/2020.07.20.212050

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