Article

Germ granule association drives small RNA specificity for a nuclear Argonaute protein

2023-08-01

Abstract excerpt

RNA interference (RNAi) is a conserved gene silencing process that exists in diverse organisms to protect genome integrity and regulate gene expression. In C. elegans , the majority of RNAi pathway proteins localize to perinuclear, phase-separated germ granules, which are comprised of sub-domains referred to as P granules, Mutator foci, Z granules, and SIMR foci. However, the protein components and function of t...

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Literature Corpus work: 84d0f899-2b96-5554-9d3d-bd6ecf10bdc0
DOI: 10.1101/2023.08.01.551545

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