Article
Genetic mutation and tumor microbiota determine heterogenicity of tumor immune signature: Evidence from gastric and colorectal synchronous cancers.
Frontiers in immunology - 1 Jan 2022
Yang Weili, Zhao Yaxing, Ge Qiongxiang, Wang Xiaoli, Jing Yang, Zhao Jingwen, Liu Gang, Huang He, Cheng Fei, Wang Xiaoxi, Ye Yulin, Song Wenjing, Liu Xinjuan, Du Juan, Sheng Jianpeng, Cao Xiaocang
Abstract excerpt
Both colorectal and gastric cancer are lethal solid-tumor malignancies, leading to the majority of cancer-associated deaths worldwide. Although colorectal cancer (CRC) and gastric cancer (GC) share many similarities, the prognosis and drug response of CRC and GC are different. However, determinants for such differences have not been elucidated. To avoid genetic background variance, we performed multi-omics...
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