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Integrative analysis of quantitative trait loci of alternative polyadenylation and GWAS highlights key regulators of milk production and immune traits in Holstein.

Animal genetics - 1 Apr 2026

Tao Xinyue, Tang Yongjie, Liu Xueqin, Ni Miaozhuo, Lai Wanyi, Chen Siqian, Yu Ying

Abstract excerpt

Understanding the genetic regulation of complex traits like mastitis in Holstein dairy cows remains a challenge, despite significant advancements in breeding techniques. This study integrates 3'-untranslated region alternative polyadenylation (APA) quantitative trait loci (3'aQTL) mapping with genome-wide association studies (GWASs) to identify key genetic variants and regulatory genes influencing traits during...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41773938
DOI: 10.1002/age.70071
PMCID: PMC12955697

Genes

GRINA
NRF1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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