Article
Identification and characterization of whole blood gene expression and splicing quantitative trait loci during early to mid-lactation of dairy cattle.
BMC genomics - 6 May 2024
Tang Yongjie, Zhang Jinning, Li Wenlong, Liu Xueqin, Chen Siqian, Mi Siyuan, Yang Jinyan, Teng Jinyan, Fang Lingzhao, Yu Ying
Abstract excerpt
BACKGROUND: Characterization of regulatory variants (e.g., gene expression quantitative trait loci, eQTL; gene splicing QTL, sQTL) is crucial for biologically interpreting molecular mechanisms underlying loci associated with complex traits. However, regulatory variants in dairy cattle, particularly in specific biological contexts (e.g., distinct lactation stages), remain largely unknown. In this study, we...
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