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Identification of novel protein biomarkers and drug targets for colorectal cancer by integrating human plasma proteome with genome

2022-12-21

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold>Proteome is a major source of therapeutic targets. We conducted a proteome-wide Mendelian randomization (MR) study to identify candidate protein markers and therapeutic targets for colorectal cancer (CRC). <bold>Methods: </bold>Protein quantitative trait loci (pQTL) were derived from seven published genome-wide association studies (GWAS) on plasma proteosome, and...

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Literature Corpus work
721aeebd-0dec-5640-9065-b17ad615490c
DOI
10.21203/rs.3.rs-2317124/v1
Open publication

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Identification of novel protein biomarkers and drug targets for colorectal cancer by integrating human plasma proteome with genomeDOI 10.21203/rs.3.rs-2317124/v1
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