Article
Causal inference in psychiatric research: how to critically evaluate and interpret mendelian randomization studies.
Molecular psychiatry - 1 Jun 2026
Garcia-Argibay Miguel, Wootton Robyn E, Larsson Henrik, Mattheisen Manuel, Polimanti Renato, Meier Sandra
Abstract excerpt
Mendelian Randomization (MR) has become an essential tool in psychiatric research offering valuable insights into the causal relationships underlying risks and consequences of psychiatric conditions. This method utilizes genetic data to infer causal effects, effectively reducing biases commonly encountered in traditional observational studies. By leveraging genetic information, MR helps to identify potential risk...
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