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Article

Assessing causal relationships using genetic proxies for exposures: an introduction to Mendelian randomization.

Addiction (Abingdon, England) - 1 Apr 2018

Katikireddi Srinivasa Vittal, Green Michael J, Taylor Amy E, Davey Smith George, Munafò Marcus R

Abstract excerpt

BACKGROUND AND AIMS: Studying the consequences of addictive behaviours is challenging, with understanding causal relationships from observational data being particularly difficult. For example, people who smoke or drink excessively are often systematically different from those who do not, are less likely to participate in research and may misreport their behaviours when they do. Furthermore, the direction of...

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Identifiers

PMID: 28921935
DOI: 10.1111/add.14038
PMCID: PMC5873430

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CHRNA5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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