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Article

Sophora tonkinensis reprograms tumor-associated macrophages to M1-like phenotype and exerts anti-hepatocellular carcinoma effects.

Molecular immunology - 1 Mar 2026

Huang Siqi, Wen Jincai, Chen Xiaoyan, Wang Xianling, Guo Yuanyuan, Liu Lu, He Caiping, Lu Zongliang, Huang Ang, Zhan Xiaoyan, Zhao Jun, Xiao Xiaohe, Bai Zhaofang

Abstract excerpt

ETHNOPHARMACOLOGICAL RELEVANCE: Sophora tonkinensis radix et rhizoma is a medicinal herb traditionally used to treat inflammatory diseases and various types of cancer, previous phytochemistry studies have identified abundant alkaloids and flavonoids as the major bioactive components with anti-inflammatory, anti-tumor, hepatoprotective and immunomodulatory pharmacological effects, but their effects on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41666700
DOI: 10.1016/j.molimm.2026.02.003

Genes

CD86
JAK1
STAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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