Article
Role of tumor-associated macrophages in the progression of hepatocellular carcinoma.
Surgery today - 1 Jan 2012
Shirabe Ken, Mano Yohei, Muto Jun, Matono Rumi, Motomura Takashi, Toshima Takeo, Takeishi Kazuki, Uchiyama Hidekaki, Yoshizumi Tomoharu, Taketomi Akinobu, Morita Masaru, Tsujitani Shunichi, Sakaguchi Yoshihisa, Maehara Yoshihiko
Abstract excerpt
Recent studies have shown that the tumor microenvironment plays an important role in cancer progression. Tumor-associated macrophages (TAMs), in particular, have been found to be associated with tumor progression. Macrophages have multiple biological roles, including antigen presentation, target cell cytotoxicity, removal of foreign bodies, tissue remodeling, regulation of inflammation, induction of immunity,...
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