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Article

Genetic dissection of transcription start site selection by RNA polymerase II in Saccharomyces cerevisiae.

Genetics - 4 Apr 2026

Arora Payal, Brennan Kieran F, Warner Marcie H, Kaplan Craig D

Abstract excerpt

Transcription initiation by RNA Pol II is driven by a preinitiation complex (PIC) comprising Pol II and general transcription factors (GTFs): TFIIA, TFIIB, TFIID, TFIIE, TFIIF, and TFIIH. In Saccharomyces cerevisiae, transcription start site (TSS) selection proceeds by a promoter scanning mechanism where the PIC scans downstream for TSSs. To determine which factors participate in TSS selection by promoter...

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Identifiers

PMID: 41642681
DOI: 10.1093/genetics/iyag034
PMCID: PMC12958465

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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